| Unlockable: | How to Unlock: |
| All cards | Successfully complete Arcade mode with all characters, and Family mode under all three difficulty settings. |
| Basilicum | Ente 1, 7, 14, 16, 5, 12, 10, 3 as a password. |
| Chikusa | Successfully complete Arcade mode as Gokureda |
| Didi and Zizi | Successfully complete Arcade mode as Lambo or I-Pin |
| Hyper Dying Will Tsuna | Successfully complete Arcade mode as Tsuna |
| Ken | Successfully complete Arcade mode as Yamamoto |
| Lancia | Successfully complete Arcade mode as Mukuro |
| M.M. | Successfully complete Arcade mode as Bianchi |
| Mukuro | Successfully complete Arcade mode as Hyper Dying Will Tsuna |
| Squalo | Successfully complete Arcade mode as Basiliscum under the Hard difficulty setting. |
